9 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... disorder, Mycoplasma, HIV ... transient hemolysis • Treatment ... #hematology #diagnosis ... #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... #oncology #hematology ... #diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Hematologic • Anemia ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Autoimmune / Inflammatory ... Chronic Fatigue Syndrome
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hemolytic anemia ... infections (Epstein-Barr ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... immunodeficiency virus (HIV ... #Syndrome #diagnosis ... #management #neurology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
and less common ... an underlying autoimmune ... and treatment can ... pachymeningitis • HIV ... #neurology #noninflammatory
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... symptoms - most common ... , HIV, rubella legionella ... #hematology #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... (NSHL) - (most common ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... Comment on type ... #hematology