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oncology blood product aplastic chronic classification cll common cvid extravascular gap globulin hemolysis hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular leukemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... and Platelet Disorders ... Diagnosis and Workup ... Diagnosis #Causes ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... #oncology #hematology ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... /or drug treatment ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... hemolytic anemia ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... , thrombocytopenia ... microglobulin Treatment ... #workup #oncology ... #hematology
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