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adultonset causes chronic disease fatigue globulin monoclonal oncology paraproteinemias proteingap stills vasculitis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... borrelia, Rubeola, HBV ... , HIV, HTLVI, Hantavirus ... #management #treatment ... #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... • Anemia • ... Malignancy Infectious ... • HIV Autoimmune ... #Diagnosis #Algorithm
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gap (Total Protein ... infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Feature A Monoclonal Protein ... Zone Lymphoma (HCV ... et diutinum Neurologic ... (-) hemolytic anemia ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... HTN • Check: HBV ... with elevated protein ... exposure or Dx of malignancy ... #Diagnosis #Rheumatology
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