24 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Risks factor for HIV ... , HCV - Alcohol ... smear, HIV/HCV ... #Causes #Workup ... #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
aspergillosis) - Viral (HIV ... - DRESS - AIN ... Hypereosinophilic Syndrome ... - Chronic Eosinophilic ... #Causes #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... DDX - Other causes ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... effusions, weight gain ... • Steroids: IV ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Most common cytopenia ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... normal/high - Chronic ... , think about common ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
weight • Chest pain ... tightness Most Common ... abnormal in adults • Blood ... , CCP, ANCA • HIV ... mycobacteria Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... #workup #oncology ... #hematology