11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... , HCV - Alcohol ... smear, HIV/HCV ... #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Campylobacter jejuni - HIV ... Diagnosis: • ... #management #treatment ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... normal CSF white blood ... and cauda equina TREATMENT ... #management #neurology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #Transfusion #diagnosis ... #management #hematology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... cord infarct • HIV ... cord • Guillain-Barre ... axial T1 and T2 Treatment ... #causes #neurology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #Transfusions #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Statins - ETOH - Infection ... - Viral (HIV, Influenza ... UA positive for blood ... #Management #causes ... #treatment #nephrology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... simplex virus, HIV ... Transverse Myelitis Treatment ... #management #neurology