13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... , HCV - Alcohol ... smear, HIV/HCV ... #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Campylobacter jejuni - HIV ... Diagnosis: • ... #management #treatment ... #neurology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #Transfusion #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #Transfusions #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... normal CSF white blood ... and cauda equina TREATMENT ... #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... • 10-20% of HIV-infected ... a decrease in HIV ... pancreatitis • HBV ... , HCV - Hepatic
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... cord infarct • HIV ... cord • Guillain-Barre ... axial T1 and T2 Treatment ... #causes #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Statins - ETOH - Infection ... - Viral (HIV, Influenza ... UA positive for blood ... #Management #causes ... #treatment #nephrology