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Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations:
1. HLH
2. Still's disease
3. Systemic

HLH 2. ... Hyperferritinemia #Algorithm #Differential

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup and Differential ... and Screen for HLH ... HLH syndrome 5. ... Pancytopenia #Workup #Differential

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup and Differential ... and Screen for HLH ... HLH syndrome 5 ... Pancytopenia #Workup #Differential

Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin

Hyperferritinemia - Differential ... HLH or Adult Onset ... saturation to differentiate ... In adults, HLH is ... Hyperferritinemia #Differential

Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory

Pancytopenia - Differential ... erythematosus • HLH ... #Pancytopenia #Differential

Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV
• EBV
• CMV
• HBV
• Dengue
• Rubella

Differential Diagnosis ... Amyloidosis • HLH ... Lymphadenopathy #Differential

Conditions Associated With Hyperferritinemia
DDx of extreme hyperferritinemia >10,000
Not just HLH - in fact, most common

10,000 Not just HLH ... Infection-Fungai - Primary HLH ... - Secondary HLH ... Hyperferritinemia #differential

Hypoplastic Left Heart Syndrome (HLHS)
• Introduction
• Embryology
• Anatomy
• Physiology of HLHS
•

Heart Syndrome (HLHS ... Physiology of HLHS ... LeftHeart #Syndrome #HLHS

Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury:
• Hepatic vein:

Liver Injury - Differential ... PBC, PSC, IgG4, HLH ... injury #hepatitis #differential

Ketosis Disorders - Comparison Table
• Starvation Ketosis
• Alcoholic Ketoacidosis (AKA)
• Diabetic Ketoacidosis (DKA)

Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... Disorders #ketones #differential

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