6593 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Presentation / Diagnosis ... Diagnosis via genetic ... • Bicytopenia Treatment ... Infection should be diagnosed ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... hemophagocytosis = additional diagnostic ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
diagnostic consideration ... recognition and treatment ... search for and treatment ... Diagnostic Criteria ... Treatment Approach
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Algorithm for treatment of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar State (HHS)

#DKA #HHS #Algorithm #Diabetic #Ketoacidosis
Algorithm for treatment ... Hyperosmolar State (HHS ... ) #DKA #HHS # ... State #management #treatment
Hypoplastic Left Heart Syndrome (HLHS)
 • Introduction
 • Embryology
 • Anatomy
 • Physiology of HLHS
 •
Heart Syndrome (HLHS ... Physiology of HLHS ... Physical Exam/Diagnostic ... LeftHeart #Syndrome #HLHS
Guideline for management of adult patients with diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS)

UCSD Internal
hyperglycemic state (HHS ... @ucsdim #DKA #HHS ... algorithm #diabetes #treatment
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS ... if HHS + poor PO ... comparison #laboratory #diagnosis
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Diagnostic Schema ... HLH 2. ... #Differential #Diagnosis
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... #differential #diagnosis