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differential hematology signs amiodarone apml arteritis capillary clarksons classification criticalcare differentiation disease encephalopathy gca giantcell induced influenza leak leukostasis lung
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Renal Syndromes ... or serologies + symptoms ... Goodpasture's cause ... #Renal #Syndromes ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
and renal abnormalities ... Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... #Rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... are not caused ... (e.g. incidental ... Pulmonary: dyspnea ... #Management #Signs
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... #management #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... = vasculitis vs ... Treatment of GCA ... them, but urgent rheumatology ... #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... the underlying cause ... • Treatment of ... with AEDs until cause ... #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... filling +++ (risk of pulmonary ... ) • IVIg 2 g/kg ... #diagnosis #management ... #rheumatology
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