10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... (e.g. incidental ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... #Management #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... recent DAN) • EMG ... or serologies + symptoms ... Goodpasture's cause ... #management #treatment
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... blood gas, 12-lead ECG ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... gradually with symptoms ... Exclude other causes ... Improvement in symptoms ... #diagnosis #management
Intraoperative Hypoxia / Desaturation / Cyanosis - Guidelines for Crises in Anaesthesia
Using these steps from start
reservoir bag and APL ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Workup ... #Management #Workup
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... #Inflammatory #Syndrome ... #Management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... filling +++ (risk of pulmonary ... ) • IVIg 2 g/kg ... #diagnosis #management ... timeline #treatment #rheumatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... When present, symptoms ... • "Vasomotor" symptoms ... transformation into MDS or AML ... #diagnosis #management