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hematology differential neurology adrenal anemia aplastic apml barre classification differentiation encephalopathy gbs guillain hodgkins insufficiency leukostasis lymphoma lysis myopathy myositis
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
and Management ... in the US: Autoimmune ... ketoconazole, etomidate) Symptoms ... hypophysitis, Sheehan's syndrome ... #Management #Endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... : >3 symptoms, or ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... Neurological symptoms ... the underlying cause ... with AEDs until cause ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... recent DAN) • EMG ... or serologies + symptoms ... Goodpasture's cause ... #management #treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... than one after symptom ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... ingestion • B symptoms ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... statins - probably caused ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... ethnicities Symptoms ... + Nonspecific symptoms ... Polychondritis #rheumatology ... #diagnosis #management
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