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anesthesiology hematology workup intraoperative anemia aplastic apml capillary cardiac clarksons differential differentiation disease embolism embolus hyperthermia ischaemia ischemia leak leukostasis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... #Differential #Causes ... Anesthesiology #Anesthesia ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
Causes: thrombus ... decreased ETCO2 Symptoms ... over 2 h (>65 kg ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is conscious, symptoms ... Anesthesiology #Anesthesia ... Intraoperative #Checklist ... #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... : >3 symptoms, or ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... tissues: Myalgia, paresthesia ... ) • IVIg 2 g/kg ... #diagnosis #management ... timeline #treatment #rheumatology
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