9 results
Calculating a Reticulocyte Index (RI)
Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction
Absolute Reticulocyte Count =
a Reticulocyte Index ... reticulocytes x Patient's Hct ... / Normal Hct ... #RI #RPI #hematology ... #diagnosis #anemia
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... NAFLD, Others • Mild ... LFTs #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Reticulocyte Production Index ... = (Retic %) x (Hct ... appropriately)- Retic Index ... #hematology #anemia ... #differential #
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
• Histology: Normal-mild ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... NAFLD • Others Mild ... Others #LFTs #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... Pregnancy #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... ALP, alkaline phosphatase ... BMI, body mass index ... #Algorithm #Hepatology ... #Differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... megakaryocytes and a normal ... • Reticulocyte index ... • Allogeneic HSCT ... #oncology #hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
Why does the Hgb/Hct ... -6% drop in Hg/Hct ... 30 min and Hg/Hct ... concentrating Hg/Hct ... Decrease of Hg/Hct