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diagnosis management blood pathophysiology product reactions algorithm anemia cancer embolism fatty hyponatremia liver nephrology obgyn obstetrics pregnancy thrombosis transfusion transfusions
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... • Allogeneic HSCT ... #Anemia #oncology ... #hematology #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... Liver #Pregnancy #hepatology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... - and IL-2- induced ... VOD following HSCT ... chemotherapy, nausea ... algorithm #nephrology #oncology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May have drop in Hct ... Causes purpura & ... TRALI): Leading cause ... due to marrow aplasia ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
May have drop in Hct ... Causes purpura & ... TRALI): Leading cause ... due to marrow aplasia ... diagnosis #management #hematology
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