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diagnosis algorithm management blood comparison lfts obstetrics pathophysiology pregnancy reactions abnormal arterial aspergillus betadglucan biomarkers cancer causes disease elevated embolism
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... acid metabolism products ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Pregnancy #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Wilsons, Pregnancy - AFLP ... NAFLD, Others • Mild ... Algorithm #diagnosis #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... NAFLD • Others Mild ... Others #LFTs #Hepatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... or other blood products ... and allogeneic HSCT ... BAL GM does not differentiate ... 100d following HSCT
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Hb>16.5 g/dL, Hct ... Hb>16.0 g/dL, Hct ... Better call hematology ... Algorithm #workup #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Syndrome, Ischemic Liver ... , IBD • COVID- ... pathophysiology #hematology ... #differential #
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... May have drop in Hct ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May have drop in Hct ... eruptions, diarrhea, liver ... Blood products contain ... of transfused products ... diagnosis #management #hematology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... - and IL-2- induced ... amyloidosis) • Liver ... VOD following HSCT ... #Hyponatremia #Differential
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