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diagnosis management pathophysiology algorithm blood oncology reactions workup activation aflp arterial bleeding cancer classification embolism fatty hemostasis hodgkins hospitalization hyponatremia
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... #Pregnancy #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Fibrin degradation products ... result in severe anemia ... immune hemolytic anemia ... WBC count and differential ... Diagnosis #Workup #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Hb>16.5 g/dL, Hct ... Hb>16.0 g/dL, Hct ... Better call hematology ... Algorithm #workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... with leukopenia, anemia ... thrombocytopenia • Liver ... Fibrin degradation products ... Diagnosis #Management #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... , IBD • COVID- ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Why does the Hgb/Hct ... -6% drop in Hg/Hct ... 30 min and Hg/Hct ... concentrating Hg/Hct ... Decrease of Hg/Hct
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... Acquired: • Mild ... discern these causes ... #Diagnosis #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
May have drop in Hct ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May have drop in Hct ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... genes and gene products ... Immunohistochemical studies (to differentiate ... classification #hematology
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