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diagnosis pathophysiology blood oncology product reactions workup aflp algorithm aplastic arterial bruising classification deficiency embolism fatty folate folicacid hemostasis hodgkins
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential ... contraceptives - HRT ... Ischemic Liver, IBD ... pathophysiology #hematology ... #differential #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... • Allogeneic HSCT ... #oncology #hematology ... #diagnosis #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... result in severe anemia ... immune hemolytic anemia ... WBC count and differential ... Diagnosis #Workup #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Hb>16.5 g/dL, Hct ... Hb>16.0 g/dL, Hct ... : neuro, heme (bleeding ... Better call hematology ... Algorithm #workup #hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Why does the Hgb/Hct ... -6% drop in Hg/Hct ... 30 min and Hg/Hct ... concentrating Hg/Hct ... Decrease of Hg/Hct
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
have hemolytic anemia ... folate that can cause ... with underlying mild ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... Liver #Pregnancy #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... associated with thrombosis ... Acquired: • Mild ... discern these causes ... #Diagnosis #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May have drop in Hct ... Causes purpura & ... cause of transfusion ... Transfusion #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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