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management guillain product reactions syndrome treatment alkaline coagulation dic differential disseminated gbs guillainbarre hepatology hyophosphatasia intravascular leukemia low oncology phosphatase
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
- Summary Acute ... AIDP that presents ... Pathophysiology ... Diagnosis: • ... management #treatment #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... involvement • 30%: CNS ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... membrane into the CNS ... deficiency • blood ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
(GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... normal CSF white blood ... the underlying pathophysiology ... #management #neurology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... incompatible blood ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... TRALI resembles ARDS ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... TRALI resembles ARDS ... #Transfusions #diagnosis ... #management #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulses, bruits, or blood ... HTN • Check: HBV ... tract, and often causes ... chorioretinitis, CNS ... #Rheumatology
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