9 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Brucellosis - Viruses: HIV ... Chikungunya - Herpes ... virus: CMV, HSV ... #physicalexam
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... borrelia, Rubeola, HBV ... Coxsackie, CMV, EBV, HIV ... Pulmonary: pleural effusion
AIDS-defining illnesses
 - Candidiasis of the esophagus, bronchi, trachea, or lungs [(but NOT the mouth (thrush)]
Cytomegalovirus disease ... Encephalopathy, HIV ... related - Herpes ... syndrome due to HIV ... Defining #Illnesses #HIV
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... Differential ... Cryoglobulins • HIV ... • HBV HCV
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... Epidural abscess - Herpes ... zoster - HIV ... extremity #msk #physicalexam
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of treatment of HIV ... • 10-20% of HIV-infected ... a decrease in HIV ... pancreatitis • HBV ... , HCV - Hepatic
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Infections in HIV ... macrophages in HIV ... low if you have HIV ... nodules possible in HIV ... Lung #Infections #HIV
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Diagnosis: • Systemic ... muscle weakness • Nerves ... HTN • Check: HBV
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
an autoimmune disease ... association with HCV ... association between HCV ... #NEJM #clinical ... #photo #lichen #