12 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
) for chronic hepatitis ... #DAAs #Antivirals ... #table #treatment ... infectiousdisease #hepatology ... #Management #Pharmacology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Diagnosis and Management ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
dechallenge • Acute or chronic ... e.g. ascites), Chronic ... hepatitis fibrosis ... • Autoimmune hepatitis ... #DILI #DrugInduced
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
disease: > 2 • NASH ... , Chronic viral ... hepatitis: < 1 ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Rash is usually ... include: infections (HSV ... the first few days ... Erythemas #comparison #table ... differential #diagnosis #dermatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... • Evolution: Chronic ... Lupusreference #druginduced ... sle #comparison #table ... #rheumatology #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... diseases and hepatitis ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
24 hours to 30 days ... maculopapular rash ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions