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diagnosis differential reactions activation algorithm anemia aplastic bloodproduct causes chemistry classification coagulation common components contents cvid dic disseminated hepatitis hodgkins
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... intestines, white blood ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... intestines, White blood ... #differential #Hepatology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... Hct 35%. 450mL blood ... Contents #Volume #Hematology ... #Management #Table
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... maculopapular rash ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... eruptions, diarrhea, liver ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... - MAHA: TTP/HUS ... DIC • Severe Liver ... causes #treatment #management ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
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