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KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
Inflammatory Cytokine Syndrome ... #IDFellowCase #ID ... #Infections #Differential ... #Ddx #Diagnosis ... #KSHV #HHV #KICS
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... Cytomegalovirus, Epstein-Barr ... Insufficiency #AI #differential
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... elevation • Nausea ... 14%), in which case ... cerebrospinal fluid DDX ... : • Epstein-Barr
Causes of Myocarditis
Infectious Etiologies:
 • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... Infectious Etiologies ... herpesvirus 6, Epstein—Barr ... Hepatitis C virus, HIV ... #Myocarditis #differential
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... : HIV, Hepatitis ... CIDP, Guillain-Barre ... Peripheral #Neuropathy #differential ... #diagnosis #causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... • Malignancy Infectious ... Tuberculosis • Epstein-Barr ... Hepatitis • HIV ... Chronic Fatigue Syndrome
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Weight loss - DDX ... Brucellosis - Viruses: HIV ... Herpes virus: CMV, HSV
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
Causes of Pericarditis - Differential Diagnosis Algorithm
Viral:
 • Coxsackie
 • Echovirus
 • Adenovirus
 • Epstein-Barr virus
- Differential ... Adenovirus • Epstein-Barr ... Cytomegalovirus • HIV ... Post-cardiac injury syndrome ... #Cardiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... : HCV infection, ... HBV infection, ... HIV infection ... DDX: • ANCA (Antineutrophil