10 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... are pulmonary • HIV ... Treatment: Active ... TST or IGRA HIV ... : • HIV-infected
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... are pulmonary • HIV ... Treatment: Active ... TST or IGRA HIV ... : • HIV-infected
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... macrophages in HIV ... low if you have HIV ... nodules possible in HIV ... #Infections #HIV
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
Threshold for treatment ... individual with active ... disease • HIV ... carcinoma of head/neck/lung ... individuals #Tuberculosis
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
of interstitial lung ... - Clinical manifestations ... legionella/strep, HIV ... Anti-dsDNA, ANCA COP DDX ... Treatment: •
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
infection • Most common ... cause: Aspiration pneumonia ... for Klebsiella pneumonia ... Lung Abscess - Clinical ... westermani • Other: TB
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
and Disease in HIV-AIDS ... be initiated in HIV-infected ... persons with clinical ... suggestive of HIV-related ... for HIV-related
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... community-acquired infections: Pneumonia ... DDX - Other causes ... Epstein-Barr syndrome, HIV
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... • 10-20% of HIV-infected ... a decrease in HIV ... pancreatitis • HBV ... , HCV - Hepatic
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis, hiv ... DDX Tb meningitis ... sign on mri) HIV-infected ... Standard treatment ... #radiology