11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Risks factor for HIV ... , HCV - Alcohol ... peripheral blood smear, HIV ... /HCV testing - ... IgA, IgG, IgM (CVID
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... to 8 years Clinical ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Causes: 1. ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Causes of spinal ... Infarction - Infection ... syphilis, and HIV ... differential #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... Transverse Myelitis - Clinical ... causes need to ... simplex virus, HIV ... diagnosis #management #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - CMV - HCV ... - HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... disease 2019 (COVID ... cryoglobulins • Negative causes ... Cryofibrinogenemia DDX ... • TTP, HUS and HIT
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Campylobacter jejuni - HIV ... like illnesses, COVID ... Guillain-Barre Clinical ... management #treatment #neurology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Mucormycosis Eschar 30 M HIV ... malnutrition, HIV ... Indiana University Infectious ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
other rickettsia) Dx ... : serology; pcr ... , hsv, Queensland ... Eschar #rakari #clinical ... photo #skinrash #dermatology