12 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Clinical Presentation ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... CTD) • ANCA (Dx ... Cryoglobulins • HIV ... • HBV HCV • ... #rheumatology #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... of the spinal cord ... parainfluenza, Coxsackie, HIV ... #Weakness #Differential ... #Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV ... disorders #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... simplex virus, HIV ... - Sjogren - Vasculitis ... diagnosis #management #neurology ... #differential
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... (IRIS): • In HIV ... Meningitis • Include: vasculitis ... and not direct infection ... Tuberculosis #diagnosis #differential
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... syndromes #lesions #differential ... #diagnosis #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... HTN • Check: HBV ... drug exposure or Dx ... Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... Cryofibrinogenemia DDX ... • TTP, HUS and HIT ... Cryofibrinogenemia #diagnosis #rheumatology