10 results
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... differential #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
disorder of the spinal ... Transverse Myelitis - Clinical ... simplex virus, HIV ... - Sjogren - Vasculitis ... diagnosis #management #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
cord and nerve ... roots Spinal Cord ... (IRIS): • In HIV ... Meningitis • Include: vasculitis ... and not direct infection
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Lesions of the spinal ... cord • Inflammatory ... Infectious: Brain ... parainfluenza, Coxsackie, HIV ... Differential #Diagnosis #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... - Due to Viral infection ... Clinical Presentation ... Mycoplasma, EBV, HIV ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... Diagnosis: • + Clinical ... Cryofibrinogenemia DDX ... • TTP, HUS and HIT
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... HTN • Check: HBV ... cognitive impairment, neurologic ... drug exposure or Dx ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... white matter, spinal ... cord, and basal ... Dx). ... signs #symptoms #rheumatology