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antibodies hematology vasculitis anca antineutrophil autoimmune chronic cll erythematosus leukemia lupus lymphocytic management monoclonal myopathy myositis paraproteinemias patterns sle symptoms
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... connective tissue disease ... 90% • Anti-GBM disease ... #Antinuclear #Antibody ... diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... Disease! ... Rheumatic Diseases ... #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... disease) Differential ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... atherosclerotic disease ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Classification: ... Diagnosis: • ANCA-associated ... tissue disease ... diseases (i.e.
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... rheumatic diseases ... atherosclerotic disease ... most important diseases ... #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... cells can indicate disease ... #workup #oncology ... #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Interstitial lung disease ... Interstitial lung disease ... Interstitial lung disease ... skeletal muscle disease ... myocarditis Other Diseases
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