Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic antinuclear ana patterns antibodies disease autoimmune arthritis anca table testing myositis rheumatic

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Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... Positive ANA ≠ Autoimmune ... Syndrome, Myositis ... #Antibodies #ANA ... #patterns #rheumatology

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

ANA Patterns and ... Diseases: • Homogeneous ... connective tissue disease ... #Antibodies #ANA ... #patterns #rheumatology

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... c-ANCA - Vasculitis ... granulomatosis p-ANCA

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

(Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... LFT • ESR • ANA ... ) pattern: antibodies

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

Rheumatology Workup ... Diseases • Septic ... connective-tissue disease ... #Disease #Rheumatoid ... #testing #Rheumatology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

findings (ANA, ... Diagnosis: • ANCA-associated ... Still disease, ... tissue disease ... rheumatologic diseases

Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain

Autoimmune Myositis ... • Anti-NXP2 (ANA ... Interstitial lung disease ... Interstitial lung disease ... skeletal muscle disease

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