12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... #patterns #rheumatology ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... cases • Sjögren syndrome ... #antibodies #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... • Systemic lupus ... lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Behçet Syndrome ... • Cogan Syndrome ... lupus erythematosus ... differential #diagnosis ... #rheumatology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... capillary leak syndrome ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... #Sjogrens #Syndrome ... #Rheumatology # ... Diagnosis #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... Lupus Erythematosus ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Differential Diagnosis ... • Behcet syndrome ... • Cogan syndrome ... #Differential #Diagnosis ... #Rheumatology