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diagnosis antinuclear antineutrophil hematology monoclonal oncology paraproteinemias pulmonary renal sle treatment types
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... cases • Sjögren syndrome ... Vasculitis: • ... Renal-limited vasculitis ... diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... lupus erythematosus ... ) pattern: antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• +ANA can be seen ... : The ANA patterns ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #ANA #patterns
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... syndrome in 80% ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... capillary leak syndrome ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Sneddon-Wilkinson disease
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... diseases with pulmonary ... Inflammatory eye disease ... palpable purpura 2/2 vasculitis ... : ANCA antibody,
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