4 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... #Related #Disease ... #phenotypes #workup
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... with auto-immune diseases ... #autoantibodies ... #rheumatology # ... table #ANA
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... anemia due to cold IgG ... Sneddon-Wilkinson disease ... #Differential #Diagnosis ... #Oncology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
95% (IgG anti-chromatin ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology # ... diagnosis #management