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management hematology lupus sle chronic cll disease erythematosus lymphocytic behcet cerebritis cns differential druginduced hemeonc igg4 mds monoclonal myelodysplasia myelodysplastic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... the formation of autoantibodies ... CNS #neurology #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... #Differential #Diagnosis ... #Oncology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Clinical history ... female, asian • Systemic ... serum lgE, no autoantibodies ... #phenotypes #workup ... #treatment #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
cytometry → >500/uL ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #oncology #hematology ... #hemeonc #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (Clinical Dx). ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Anti-Ro/SSA autoantibodies ... Clinical Features ... Hodgkin lymphoma and leukemia ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... #diagnosis #hematology ... #oncology
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