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diagnosis vasculitis lupus sle ana antibodies antineutrophil antinuclear arthritis comparison cryoglobulinemia cryoglobulins differential druginduced laboratory management rheumatic rheumatoid size table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... lupus erythematosus ... connective tissue disease ... 90% • Anti-GBM disease ... #diseases
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... small vessels - ANCA-associated ... lupus erythematosus ... induced by chronic ... Vessels #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Classification: ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... months to years) Systemic ... Lupus Erythematosus ... • Evolution: Chronic ... disease Dr.
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... cytoplasmic antibody ... lupus erythematosus ... #rheumatology #
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