346 results
Insulin Pharmacology and Conversion

 • Conversion of U-100 to U-500 Insulin
 • Inpatient Intravenous to subcutaneous
Insulin Pharmacology ... U-100 to U-500 Insulin ... subcutaneous (s/c) insulin ... @DharSaty #Insulin ... Duration #timeline #halflife
Insulin and analogues onset of action, peak times and duration.

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#pharmacology #table #comparison
Insulin and analogues ... comparison #dosing #insulin ... #medications #halflife
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Ketoacidosis (DKA ... HHS) Absolute Insulin ... Type I DM: No insulin ... stresses that ↑ insulin ... Polydipsia #dka
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
and Euglycemic DKA ... for euglycemic DKA ... • Increased insulin ... and surgery) • Insulin ... SGLT2 #Euglycemic #DKA
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... Continue insulin ... and subcutaneous insulin ... #DKA #EDKA #Insulin
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS = insulin ... restart any home insulin ... look like overlap DKA
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... Insulin is the primary ... the absence of insulin ... In DKA, the normal
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... ketoacidosis (DKA ... caused by complete insulin ... • Euglycemic DKA ... HHS) - partial insulin