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diagnosis neurology symptoms hematology acromegaly caudaequina comatose differential excess gh gravis growthhormone hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis myasthenia myelitis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Management Summary ... survival is 93-95% Pathophysiology ... symptoms are not caused ... anterior/posterior MSK ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... Myasthenia Crises ... Gravis #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
macrognathia), ↑ hand ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... or refractory cases ... #Endocrinology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Bilateral signs ... • Infectious causes ... Myelitis #diagnosis #management
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... Casey Albin MD @ ... caseyalbin #PhysicalExam
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
management. ... hyperinflammatory syndrome ... caused by uncontrolled ... Presentation • Common Signs ... Pathophysiology
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