12 results
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... signs • Glomerulonephritis ... • Cardio-renal syndrome ... #Injury #AKI #Workup
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... reflexes) • Urinary ... #MSK #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Bladder retention -> Primarily ... hemicord lesion -> Primarily ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... signs of end-organ ... renal bruit or signs ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... cholangitis #diagnosis #workup
COPD phenotypes:  Blue Bloaters vs. Pink Puffers
The two most stereotypical forms of COPD are pink
The primary life-threat ... have an overlap syndrome ... obesity-hypoventilation syndrome ... airflow obstruction causes ... #BlueBloaters #Comparison
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... anterior/posterior MSK ... Specific sarcoidosis syndromes ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... , oral cavity) Caused ... not a feature of primary ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... Workup: • Serum ... or refractory cases ... Diagnosis #Management #Endocrinology