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diagnosis neurology signs symptoms causes hematology physicalexam summary algorithm barre deficiency disease gastroenterology hemophagocytic hlh lymphohistiocytosis msk nephrology nutrition pediatrics
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Decreased / Absent Reflexes ... Paresthesias: Hands ... #diagnosis #management
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
constipation Differential ... Tethered cord • Guillain-Barre ... wink test - reflex ... T2 Treatment ... #differential #
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
While the pathophysiology ... an involuntary reflex ... Video by Dr. ... #Meningitis #Clinical ... #Video #PhysicalExam
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 Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings ... Anterior Cord Syndrome ... rectal reflex. ... #diagnosis #pathophysiology ... #signs #symptoms
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
causes such as reflex ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... The treatment strategy
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... depressed deep tendon reflexes ... the underlying pathophysiology ... cauda equina TREATMENT ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Clinical Findings ... mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology
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