21 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings ... clumsiness in hands ... rectal reflex. ... #signs #symptoms ... #msk #orthopedics
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
While the pathophysiology ... an involuntary reflex ... Video by Dr. ... #Meningitis #Clinical ... #Pediatrics #Peds
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... clinical findings ... Signs/Symptoms ... #genetics #pathophysiology ... #peds #pediatrics
Positive Hoffmann's sign (finger flexor reflex)

Flexion and adduction of the thumb and flexion of the index
Positive Hoffmann's sign ... (finger flexor reflex ... #clinical #hand ... #video #physicalexam ... #msk #orthopedics
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings ... mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... involved) - Tendon reflex ... in deep tendon reflexes ... unilateral) #SpinalCord ... #lesions #differential
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
causes such as reflex ... carotid sinus syndrome ... syncope (ruling out differential ... orthostatic vital sign ... should be guided by clinical
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... signs below the ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... #spinal #cord #spinalcord
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... immunosuppressants - Meds