27 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... syndrome, caused ... #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... injury) • Neurologic ... (Clinical Dx). ... diagnosis #management #signs ... #symptoms #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... vasculitis #Dermatologic ... rash #diagnosis #rheumatology
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
vasculitis - Skin ... Abnormal pathergy test ... Most Common Clinical ... Wide variety of skin ... #criteria #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... -74%] • Blood tests ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... the best response ... skin disease. ... #Rheumatology # ... diagnosis #management #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... folds (a fold of skin ... #Downs #Syndrome ... #PhysicalExam # ... Features #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... retinopathy Lab Tests ... differential #diagnosis #rheumatology