10 results
A 48-year-old-man presented to the dermatology clinic with a whitish discoloration and hyperkeratosis of the first
the dermatology clinic ... to the distal nail ... Microscopic examination ... #Clinical #IM #InfectiousDisease ... RapidProgression #NEJM
Brittle nails and hair loss in hypothyroidism- ...Physical examination revealed dry skin, thickened and brittle nails
Brittle nails and ... brittle nails with ... brittle nails and ... #clinical #photo ... #NEJM #hypothyroidism
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
was performed, and ... under polarized microscopy ... #amyloidosis #clinical ... #photo #AL #lightchain ... #NEJM
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
of the finger nails ... side effect, only cutaneous ... #flecainide #cutaneous ... #sideeffects #clinical ... #photo #nails #
Koilonychia in Iron-Deficiency Anemia- A 54-year-old woman presented to the primary care clinic with fatigue and
the primary care clinic ... nails (koilonychia ... Panel B) of both hands ... #NEJM #clinical ... #photo #koilonychia
Disseminated Cutaneous Blastomycosis- A fungal culture of skin tissue was negative; however, a skin biopsy showed
Disseminated Cutaneous ... neutrophilic abscesses, and ... of disseminated cutaneous ... #clinical #photo ... #derm #NEJM #cutaneous
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... fungal stain of clinical ... “plaque-like” cutaneous ... infection • Cutaneous ... vagina, fingers, nails
Cutaneous Actinomycosis - the left knee was noted to have edema, erythema, hyperpigmentation, hyperkeratinization, and several
Cutaneous Actinomycosis ... organism (Panel C) #Clinical ... Pathology #Rash #Cutaneous ... SplendoreHoeppli #Microscopy ... #NEJM
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... skin (xerosis) • Cutaneous ... lubricants • Pharmacologic
Corrigan’s Pulse and Quincke’s Pulse- ...While the patient was sitting upright, the right carotid artery was
Corrigan’s Pulse and ... s index finger and ... as well as the nail ... #clinical #photo ... #NEJM #corrigans