Brittle nails and hair loss in hypothyroidism- ...Physical examination revealed dry skin, thickened and brittle nails with horizontal ridges (Panel A), marked hair loss with coarse hair (Panel B), and a diffusely enlarged thyroid gland....Hypothyroidism due to Hashimoto’s (chronic lymphocytic) thyroiditis was diagnosed. Hypothyroidism should be considered in the differential diagnosis of thickened and brittle nails and hair loss, although this extreme presentation is atypical. Five years after the initiation of levothyroxine therapy, the nail changes and hair loss had resolved (Panels C and D, respectively). #clinical #photo #NEJM #hypothyroidism #hair #loss #brittle #nails
