6 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle ... blood vessels leading ... Crises can be precipitated ... The underlying pathophysiology ... SickleCell #Crisis #Features
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... • Key Features ... progressive organ dysfunction ... complement • Classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• Pathophysiology ... BIOLOGICAL FEATURES ... risk death), T-cell ... COMMON CAUSES + ... CLINICAL FEATURES
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... and increased B-cell ... tissue: Epithelioid cells ... failure Clinical Features
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... Alterations: - Sensory features ... Autonomic Dysfunction ... Pleocytosis > 100 cells
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... : LCH exhibits features ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... for endocrine dysfunctions