10 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Retinoblastoma Signs ... partial retinal red reflex ... accumulation - Decreased ... Retinoblastoma #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... Infertility • Decr Bone ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics ... #Peds
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... pain, numbness, decreased ... reflexes Pathophysiology
Plantar Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect of the
extension of the great toe ... toes or “Babinski sign ... Primitive #Babinski #Reflex ... #PhysicalExam #clinical ... #video #peds #pediatrics
Primitive Suck, Rooting Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect
extension of the great toe ... toes or “Babinski sign ... Rooting #Primitive #Reflex ... #PhysicalExam #clinical ... #video #peds #pediatrics
Floppy Baby Syndrome
 • Infantile Botulism
 • Acute Flaccid Myelitis
 • Guillain Barre
 • Neonatal Myasthenia
Myasthenia Gravis Clinical ... Presentation • Decreased ... LMN signs - Assess ... strength, tone, ... resistance, reflexes
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
if they have no clinical ... lack of tapering, decreased ... and lab signs ( ... #Diagnosis #Peds ... #Pediatrics #Kawasaki
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... Change in clinical ... Cataract Plan for Meds ... are needed: • HgbA1c ... or death (CARP, DECREASE
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... Cauda equina- decreased ... muscle tone, areflexia ... differential #algorithm