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diagnosis differential causes liver injury saag workup albumin chemistry cholangitis druginduced gradient hepatitis hepatomegaly hypertension interpretation lfts portal rvalue transaminitis
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
protein ≤ 2.5 g/dL: Cirrhosis ... protein ≥ 2.5 g/dL: Heart ... failure/constrictive ... syndrome SAAG < 1.1: Biliary ... albumin #gradient #hepatology
Primary Biliary Cirrhosis (PBC) - Diagnosis Algorithm #Primary #Biliary #Cirrhosis #PBC #Diagnosis #Algorithm #hepatology
Primary Biliary ... Cirrhosis (PBC) ... #Primary #Biliary ... #Cirrhosis #PBC ... #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... 10% Congestive heart ... failure - 3-5% ... , Pancreatic, Biliary ... Differential #Diagnosis #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Hepatic: • Cirrhosis ... • Acute liver failure ... • Primary biliary ... Post-Hepatic: • Heart ... #Hepatology #causes
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... #PBC #Primary ... #Biliary #Cirrhosis ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Congestive • Right Heart ... Failure • Budd-Chiari ... Biliary Cirrhosis ... #Causes #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... biliary cholangitis ... , Primary sclerosing ... disorder (e.g. ascites ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary ... biliary cirrhosis ... disease Congestive heart ... failure (chronic ... #Differential #Hepatology
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 Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... /Liver failure ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... kidneys • LDH: Heart ... #hepatology
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