16 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... non-muscle myosin heavy ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... afibrinogenemia, which will have ... count and platelet ... #disorders #hematology ... #differential #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... hematemesis, melena, heavy ... #Diagnosis #Causes ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... with or without platelet ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... more diffuse, can have ... Classification #pathophysiology ... #Hematology #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... deficiency Work ... Algorithm #Causes #dermatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... with previously stable ... CPAP, most pts have ... Neurologic disorders
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... minimal tumor burden Diagnosis ... →several RCTs have ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... lymphoproliferative disorders ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology ... #hematology