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diagnosis differential management algorithm chronic leukemia lymphocytic monoclonal platelet testing causes cell classification common cvid defects disease gammopathy gap globulin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... hematemesis, melena, heavy ... changes), high MCV anemia ... not required in all ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... leukemia in adults • Disorder ... →several RCTs have ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... immunoglobulin heavy-chain ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... general feeling of ill ... , breast CA - Hematologic ... Syndrome #diagnosis #dermatology ... #oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... the presence of anemia ... metabolic or endocrine disorders ... #laboratory #workup
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... non-muscle myosin heavy ... Platelet #Defects #comparison ... differential #diagnosis #hematology
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