10 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... light chain vs. heavy ... #Significance #MGUS ... Differential #Diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... disorder characterized ... immunoglobulin heavy-chain ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
MGCSMGRS ... • CLL & MBL • Heavy ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
due to a lack of GP ... MYH9-Related Disorder ... non-muscle myosin heavy ... Platelet #Defects #comparison ... differential #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... immunophenotype Clinical ... →several RCTs have ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... • Exposure to heavy ... Syndromes #diagnosis #hematology ... #oncology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... Biopsy: Solitary disorder ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology