7 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Autoimmune • ITP • SLE ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... DIC • Vasculitis ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Clinical Features ... #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
smear, HIV/HCV testing ... test, ANA (e.g., SLE ... anti-phospholipid antibodies ... (CVID, WAS), (neurologic ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... Consider RBC membrane disorder ... #workup #hematology ... #testing
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Lymphoproliferative Disorders ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... Positive Coombs testing ... hemolytic #anemia #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... double-stranded DNA antibodies ... ANA and RF (if clinical ... #Rheumatology