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activation arterial autoimmune cryofibrinogenemia dermatology disorders history macrophage management myopathy myositis nonpalpable palpable pathophysiology peds primarycare purpura syndrome thrombosis vascular
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Testosterone - Coumadin skin ... Syndrome, Ischemic Liver ... atherosclerotic lesions ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... thrombocytopenia • Liver ... 10,000 ng/mL • Hyponatremia ... #Management #Hematology ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... processes: • Systemic ... DIC • Septic emboli ... #rheumatology # ... hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
— haemophilias may ... • Presence of systemic ... and skin haemorrhage ... History #peds #pediatrics ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... lesions) • Anti-TIF1 ... • Conduction system ... Myositis #Myopathy #rheumatology
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