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diagnosis hematology differential algorithm anemia basophilia basophils causes chronic classification diseases eosinophil eosinophilia gap globulin hemolytic hodgkins leukemia lung lymphocytic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... CLL Epidemiology ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... causes are asthma, allergy ... #Algorithm #Differential ... #diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... total white blood cell ... similarly to mast cells ... released during an allergic ... Myeloproliferative Disorders
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... blood count with differential ... #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Algorithm • Sickle cells ... Consider sickle cell ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... Eosinophilic GI Disorders ... Causes: • Mast cell ... #Diagnosis #hematology ... #allergy
Upper Lobe Lung Diseases - STAR CHASERS Mnemonic S - Silicosis T - Tuberculosis A - Ankylosing Spondylitis R -
granulomatous disorders ... Silicosis - Coal worker ... pneumonitis - Allergic ... - Langerhans cell ... lung #diseases #differential
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... #Solitary #Cell ... #Diagnosis #Workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... Connective tissue disorders ... Thalassemia, Sickle cell ... Gap #ProteinGap #differential
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